This research aims to demonstrate Caesar's law to protect civilians in Syria and its effect on the social and economic circumstances of millions of Syrians stuck in their country because of the state of the siege imposed by the law's sanctions. The question tries to focus on how the law can achieve its human aims under the negative economic consequences it has on civilians, relying on the new political economy approach. It tried to interpret the non-economic activity of politicians under the Economy cover. Accordingly, The United States continues to tighten its hold on the Syrian system to exercise pressure on Syria, and to make political compromises and start significant political reforms immediately. Still, the direct targeting of Syrian economic structures through the law-imposed blockade has isolated the Syrian regime and cut off all official economic ties externally. It is encouraging the escalation of dealings with informal mediators, which has led to a sharp collapse in the Syrian Lira and a significant increase in consumer prices, which has been reflected negatively on the social reality in the light of the marked increase in poverty rates.
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